NDLI: A Convenient Synthesis of N1-Substituted 3,4-Dihydropyrimidin-2(1H)-ones by Cyclocondensation of α-Chlorobenzyl Isocyanates with Ethyl N-alkyl(aryl)-β-aminocrotonates

Content Provider	Scilit
Author	Vovk, Mykhaylo Sukach, Volodymyr Bol’But, Andriy Sinitsa, Anatoliy
Copyright Year	2006
Description	A new convenient approach to the synthesis of N1-substituted 3,4-dihydropyrimidin-2(1H)-ones was developed using the regioselective cyclocondensation of α-chlorobenzyl isocyanates with ethyl N-alkyl(aryl)-β-aminocrotonates. A number of N1-aryl and N1-alkyl substituted Biginelli compounds difficult to obtain by other methods were prepared with high yields.
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-926241.pdf
Ending Page	0378
Page Count	4
Starting Page	0375
ISSN	09365214
e-ISSN	14372096
DOI	10.1055/s-2006-926241
Journal	Synlett
Issue Number	03
Volume Number	2006
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	2006-02-06
Access Restriction	Open
Subject Keyword	Organic Chemistry Cyclocondensation Α-chloroalkyl Isocyanates Dihydropyrimidones Β-aminocrotonic Esters
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry

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