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A Systematic Review of Molecular Autopsy Studies in Sudden Infant Death Cases
| Content Provider | Scilit |
|---|---|
| Author | Martin, Lorna Jean Ramesar, Raj Heathfield, Laura Jane |
| Copyright Year | 2018 |
| Description | Sudden unexpected death is an upsetting event, which can remain unexplained even after post-mortem investigation. Internationally, molecular autopsies have shown to resolve up to 44% of unexplained cases; however, it is currently unclear how many of these were infants. This systematic literature review showed that significantly fewer infant cases were resolved (median: 4%) compared with cohorts of 1 to 45 years old (median: 32%). Further, no study involving indigenous African participants has yet been published. Overall, molecular autopsies hold immense value to living family members and is motivation to explore new avenues in infant cohorts. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1668079.pdf |
| Ending Page | 149 |
| Page Count | 7 |
| Starting Page | 143 |
| ISSN | 21464596 |
| DOI | 10.1055/s-0038-1668079 |
| Journal | Journal of Pediatric Genetics |
| Issue Number | 04 |
| Volume Number | 07 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2018-08-18 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of Pediatric Genetics Legal Medicine Sudden Infant Death Syndrome Negative Autopsy Medico-legal Investigation |
| Content Type | Text |
| Resource Type | Article |
| Subject | Genetics (clinical) Pediatrics, Perinatology and Child Health |