NDLI: 2,4-Dimethoxybenzyl Group for the Protection of Tetrazole: An Efficient Synthesis of Olmesartan Medoxomil through C

Content Provider	Scilit
Author	Seki, Masahiko
Copyright Year	2015
Description	The 2,4-dimethoxybenzyl (DMB) group was found to be effective for protecting tetrazoles. The DMB group is inert to various conditions, including those for ruthenium-catalyzed C–H arylation, but is readily cleaved under mild conditions. The use of a DMB protecting group permitted a synthesis of highly functionalized olmesartan medoxomil in a few steps.
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0034-1378848.pdf
Ending Page	2990
Page Count	6
Starting Page	2985
ISSN	00397881
e-ISSN	1437210X
DOI	10.1055/s-0034-1378848
Journal	Synthesis
Issue Number	19
Volume Number	47
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	2015-07-10
Access Restriction	Open
Subject Keyword	Journal: Synthesis Organic Chemistry Protecting Groups
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Catalysis

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2,4-Dimethoxybenzyl Group for the Protection of Tetrazole: An Efficient Synthesis of Olmesartan Medoxomil through C–H Arylation