Loading...
Please wait, while we are loading the content...
Similar Documents
Multisystem Inflammatory Syndrome in Children Admitted to a Tertiary Pediatric Intensive Care Unit
| Content Provider | Scilit |
|---|---|
| Author | Gün, Emrah Kendirli, Tanıl Botan, Edin Türker, Nazmiye Gurbanov, Anar Balaban, Burak Gencay, Ali Genco Arga, Gül Karagözlü, Selen Ramoglu, Mehmet Gökhan Özdemir, Halil Ucar, Tayfun Tutar, Ercan Ciftci, Ergin |
| Copyright Year | 2021 |
| Description | Background Multisystem inflammatory syndrome in children (MIS-C) is characterized by persistent fever, abdominal pain, vomiting, diarrhea, rash, conjunctivitis, headaches, and mucocutaneous manifestations and it can cause circulatory dysfunction, resulting in hypotension, shock, and end-organ injury in the heart and other organs and possibly death. In this study, we aimed to analyze the clinical spectrum, treatment options and outcomes of children with MIS-C who were admitted to our pediatric intensive care (PICU). Materials and Methods Clinical and laboratory findings and treatment of the patients admitted to the PICU with MIS-C between April 2020 and January 2021 were recorded, and their outcomes were evaluated. Results Nineteen patients with a median age of 12.5 years (interquartile range (IQR): 5.8–14.0 years) were admitted. Eleven (57.8%) were males. The most frequent clinical and laboratory features were fever (100%), abdominal pain (94.7%), rash (63.1%), headache (68.4%), diarrhea (47.3%), seizure (10.5%), cardiac dysfunction (52.6%), acute kidney injury (26.3%), lymphopenia (84.2%), and thrombocytopenia (36.8%). However, 8 patients needed mechanical respiratory support, 11 patients needed inotropes, 2 patients needed plasma exchange, and 1 patient needed continuous renal replacement therapy. All patients received corticosteroids, 17 patients (89.2%) received intravenous immunoglobulin, 2 patients received anakinra, 10 patients received acetylsalicylic acid, and 6 patients received enoxaparin. Median PICU length of stay was 3 days (IQR: 2–5) and only one patient died. Conclusion In conclusion, MIS-C may present with a variety of clinical manifestations, and it can lead to life-threatening critical illness. Most children need intensive care and the response to immunomodulation is usually favorable. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1733943.pdf |
| ISSN | 21464618 |
| DOI | 10.1055/s-0041-1733943 |
| Journal | Journal of Pediatric Intensive Care |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2021-08-11 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of Pediatric Intensive Care Multisystem Inflammatory Syndrome in Children Pediatric Intensive Care |
| Content Type | Text |
| Resource Type | Article |
| Subject | Critical Care and Intensive Care Medicine Pediatrics, Perinatology and Child Health |
