NDLI: A Convenient Catalytic Asymmetric Conjugate Addition Reaction to Enones Using Alkylzirconium Reagents

Content Provider	Scilit
Author	Fletcher, Stephen P. Maksymowicz, Rebecca M. Sidera, Mireia
Editor	Roth, Philippe M. C.
Copyright Year	2013
Description	Alkylzirconium reagents undergo highly enantioselective copper-catalysed 1,4-addition reaction to cyclic enones. These reactions use alkylmetal species generated in situ from alkenes and the Schwartz reagent, and do not require premade organometallic reagents. The reactions have been performed on practical synthetic scales (2.5 mmol) and a scale-up to 10 mmol is demonstrated. The reactions proceed at room temperature, in a variety of solvents, and tolerate many functional groups.
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0033-1339485.pdf
Ending Page	2668
Page Count	7
Starting Page	2662
ISSN	00397881
e-ISSN	1437210X
DOI	10.1055/s-0033-1339485
Journal	Synthesis
Issue Number	19
Volume Number	45
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	2013-07-24
Access Restriction	Open
Subject Keyword	Journal: Synthesis Organic Chemistry Asymmetric Catalysis Michael Addition Schwartz Reagent
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Catalysis

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

A Convenient Catalytic Asymmetric Conjugate Addition Reaction to Enones Using Alkylzirconium Reagents