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Liver Transplantation in Europe for Patients with Acute Liver Failure
| Content Provider | Scilit |
|---|---|
| Author | Bismuth, Henri Samuel, Didier Castaing, Denis Williams, Roger Pereira, Stephen |
| Copyright Year | 1996 |
| Description | Approximately 11% of all liver transplants performed in Europe are for acute liver failure, with one-year patient survival rates ranging between 50% and 75%. This review summarizes the selection, perioperative management, and outcome of patients transplanted for acute liver failure, with particular reference to the experience at the Hôpital Paul Brousse in Paris and at King's College Hospital, London. In both centers, the decision to proceed to liver transplantation is based on criteria that predict a survival of less than 20% with medical management alone. Infectious complications and cerebral edema remain the most common causes of death, and highlight the importance of intensive monitoring and early treatment of perioperative complications. In selected patients, auxiliary partial orthotopic liver transplantation may be a therapeutic option, with the potential for native liver generation and eventual immunosuppression withdrawal in approximately two-thirds of patients. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-1007254.pdf |
| Ending Page | 425 |
| Page Count | 11 |
| Starting Page | 415 |
| ISSN | 02728087 |
| e-ISSN | 10988971 |
| DOI | 10.1055/s-2007-1007254 |
| Journal | Seminars in Liver Disease |
| Issue Number | 04 |
| Volume Number | 16 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 1996-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Seminars in Liver Disease Key Wordsauxiliary Liver Transplantation Fulminant Hepatic Failure |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hepatology |