NDLI: A Novel Microwave-assisted One-pot Synthesis of Pyrano[2,3-d]pyrimidines and Pyrido[2,3-d]pyrimidines via a Three Component Reaction in Solvent-Free Condition

Content Provider	Scilit
Author	Bhuyan, Pulak J. Devi, Ipsita
Copyright Year	2003
Description	Three-component cyclocondensation of barbituric acids 1, triethylorthoformate 2 and alkyl nitriles 3 in presence of acetic anhydride proceeds under microwave-assisted conditions to give pyrano[2,3-d]pyrimidines 4 in excellent yields. 6-Aminouracils 5 or 6-hydroxy-aminouracils 7 react with 2 and 3 under identical conditions to yield pyrido[2,3-d]pyrimidines 6 or pyrido[2,3-d]pyrimidine oxides 8 in high yields.
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2003-43367.pdf
Ending Page	0286
Page Count	4
Starting Page	0283
ISSN	09365214
e-ISSN	14372096
DOI	10.1055/s-2003-43367
Journal	Synlett
Issue Number	2
Volume Number	2004
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	2003-12-18
Access Restriction	Open
Subject Keyword	Organic Chemistry Solvent-free Reaction Multicomponent Reaction microwave-assisted Reaction
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry

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A Novel Microwave-assisted One-pot Synthesis of Pyrano[2,3-d]pyrimidines and Pyrido[2,3-d]pyrimidines via a Three Component Reaction in Solvent-Free Condition