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A Facile and Expeditious One-Pot Synthesis of α-Keto-1,3,4-oxadiazoles
| Content Provider | Scilit |
|---|---|
| Author | Kumar, Dalip Pilania, Meenakshi Arun, V. Mishra, Bhupendra |
| Copyright Year | 2014 |
| Description | An efficient and high-yielding protocol for the preparation of α-keto-1,3,4-oxadiazoles has been developed. Formation of α-keto-1,3,4-oxadiazoles involves the 2-iodoxybenzoic acid/tetraethylammonium bromide mediated oxidative cyclization of hydrazide-hydrazones generated in situ from the reaction of aryl glyoxal and hydrazides. This one-pot protocol is reasonably general for the preparation of α-keto-1,3,4-oxadiazoles under mild conditions in short reaction times. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0033-1340981.pdf |
| Ending Page | 1141 |
| Page Count | 5 |
| Starting Page | 1137 |
| ISSN | 09365214 |
| e-ISSN | 14372096 |
| DOI | 10.1055/s-0033-1340981 |
| Journal | Synlett |
| Issue Number | 08 |
| Volume Number | 25 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2014-03-24 |
| Access Restriction | Open |
| Subject Keyword | Journal: Synlett Organic Chemistry Nitrogen Heterocycles Hypervalent Iodine Reagents |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry |