NDLI: Flexible Two-Stage Designs: An Overview

Content Provider	Scilit
Author	Brannath, W. Posch, M. Bauer, P.
Copyright Year	2001
Description	In this overview we introduce the basic ideas behind a new flexible approach in sequential designs. The different concepts based on two-stage combination tests and conditional error functions are brought together. We sketch the construction of p-values, confidence intervals, and median unbiased estimates. Finally, recursive combination tests are introduced which extend the flexibility to the choice of the number of interim analyses.
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1634472.pdf
Ending Page	121
Page Count	5
Starting Page	117
ISSN	00261270
e-ISSN	2511705X
DOI	10.1055/s-0038-1634472
Journal	Methods of Information in Medicine
Issue Number	02
Volume Number	40
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	2001-01-01
Access Restriction	Open
Subject Keyword	Journal: Methods of Information in Medicine Statistics and Probability Adaptive Design Midtrial Design Modification Two-stage Combination Test Conditional Error Function Confidence Interval Recursive Combination Test
Content Type	Text
Resource Type	Article
Subject	Health Information Management Advanced and Specialized Nursing Health Informatics

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Flexible Two-Stage Designs: An Overview