NDLI: Near-infrared fluorescent imaging techniques for the detection and preservation of parathyroid glands during endocrine surgery

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Near-infrared fluorescent imaging techniques for the detection and preservation of parathyroid glands during endocrine surgery

Content Provider	Scilit
Author	Demarchi, Marco Stefano Karenovics, Wolfram Bédat, Benoît Triponez, Frédéric
Copyright Year	2021
Abstract	Objectives In over 30% of all thyroid surgeries, complications arise from transient and definitive hypoparathyroidism, underscoring the need for real-time identification and preservation of parathyroid glands (PGs). Here, we evaluate the promising intraoperative optical technologies available for the identification, preservation, and functional assessment of PGs to enhance endocrine surgery. Methods We performed a review of the literature to identify published studies on fluorescence imaging in thyroid and parathyroid surgery. Results Fluorescence imaging is a well-demonstrated approach for both in vivo and in vitro localization of specific cells or tissues, and is gaining popularity as a technique to detect PGs during endocrine surgery. Autofluorescence (AF) imaging and indocyanine green (ICG) angiography are two emerging optical techniques to improve outcomes in thyroid and parathyroid surgeries. Near-infrared-guided technology has significantly contributed to the localization of PGs, through the detection of glandular AF. Perfusion through the PGs can be visualized with ICG, which can also reveal the blood supply after dissection. Conclusions Near infrared AF and ICG angiography, providing a valuable spatial and anatomical information, can decrease the incidence of complications in thyroid surgery.
Related Links	https://www.degruyter.com/document/doi/10.1515/iss-2021-0001/pdf
e-ISSN	23647485
DOI	10.1515/iss-2021-0001
Journal	Innovative Surgical Sciences
Language	English
Publisher	Walter de Gruyter GmbH
Publisher Date	2021-07-30
Access Restriction	Open
Subject Keyword	Innovative Surgical Sciences Otorhinolaryngology Autofluorescence Fluorescence Hypoparathyroidism Indocyanine Green Angiography Near-infrared-guided Surgery Parathyroid Glands Thyroid Surgery Journal: Innovative Surgical Sciences
Content Type	Text
Resource Type	Article

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