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Age- and sex-specific reference limits for creatinine, cystatin C and the estimated glomerular filtration rate
| Content Provider | Scilit |
|---|---|
| Author | Hannemann, Anke Friedrich, Nele Dittmann, Kathleen Spielhagen, Christin Wallaschofski, Henri Völzke, Henry Rettig, Rainer Endlich, Karlhans Lendeckel, Uwe Stracke, Sylvia Nauck, Matthias |
| Copyright Year | 2011 |
| Abstract | Early detection of patients with chronic kidney disease is of great importance. This study developed reference limits for serum creatinine and serum cystatin C concentrations and for the estimated glomerular filtration rate (eGFR) in healthy subjects from the general population aged 25–65 years.This study defined a reference population including 985 subjects from the first follow-up of the Study of Health in Pomerania. Serum creatinine was measured with a modified kinetic Jaffé method. Serum cystatin C was measured with a nephelometric assay. The eGFR was calculated from serum creatinine according to the Cockcroft-Gault (eGFRThe reference limits for serum creatinine (men: 1.11–1.23 mg/dL; women: 0.93–1.00 mg/dL) and serum cystatin C levels (men: 0.92–1.04 mg/L; women: 0.84–1.02 mg/L) increased with advancing age. The reference limits for eGFR decreased with increasing age (eGFRThis study presents age- and sex-specific reference limits for five measures of renal function based on quantile regression models. |
| Related Links | http://www.degruyter.com/downloadpdf/j/cclm.2012.50.issue-5/cclm.2011.788/cclm.2011.788.xml |
| Ending Page | 926 |
| Page Count | 8 |
| Starting Page | 919 |
| ISSN | 14346621 |
| e-ISSN | 14374331 |
| DOI | 10.1515/cclm.2011.788 |
| Journal | Clinical Chemistry and Laboratory Medicine (CCLM) |
| Issue Number | 5 |
| Volume Number | 50 |
| Language | English |
| Publisher | Walter de Gruyter GmbH |
| Publisher Date | 2011-11-14 |
| Access Restriction | Open |
| Subject Keyword | Clinical Chemistry and Laboratory Medicine (cclm) Medical Laboratory Technology Creatinine Cystatin C Glomerular Filtration Rate Population-based Study Reference Limits Study of Health in Pomerania Journal: Clinical Chemistry and Laboratory Medicine (CCLM), Vol- 50, Issue- 1 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry (medical) Clinical Biochemistry |
