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The role of prefrontal cortex in psychopathy

Content Provider	Scilit
Author	Koenigs, Michael
Copyright Year	2012
Abstract	Psychopathy is a personality disorder characterized by remorseless and impulsive antisocial behavior. Given the significant societal costs of the recidivistic criminal actixadvity associated with the disorder, there is a pressing need for more effective treatment strategies and, hence, a better understanding of the psychobiological mechanisms underlying the disorder. The prefrontal cortex (PFC) is likely to play an important role in psychopathy. In particular, the ventromedial and anterior cingulate sectors of PFC are theorized to mediate a number of social and affective decision-making functions that appear to be disrupted in psychopathy. This article provides a critical summary of human neuroimaging data implicating prefrontal dysfunction in psychopathy. A growing body of evidence associates psychopathy with structural and functional abnormalities in ventromedial PFC and anterior cingulate cortex. Although this burgeoning field still faces a number of methodological challenges and outstanding questions that will need to be resolved by future studies, the research to date has established a link between psychopathy and PFC.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937069/pdf http://www.degruyter.com/downloadpdf/j/revneuro.2012.23.issue-3/revneuro-2012-0036/revneuro-2012-0036.xml
Ending Page	262
Page Count	10
Starting Page	253
ISSN	03341763
e-ISSN	21910200
DOI	10.1515/revneuro-2012-0036
Journal	Reviews in the Neurosciences
Issue Number	3
Volume Number	23
Language	English
Publisher	Walter de Gruyter GmbH
Publisher Date	2012-01-01
Access Restriction	Open
Subject Keyword	Reviews in the Neurosciences Behavioral Sciences Anterior Cingulate Cortex Antisocial Personality Disorder Crime Decision-making Emotion Neuroimaging Ventromedial Prefrontal Cortex Journal: Reviews in the Neurosciences, Issue- 2
Content Type	Text
Resource Type	Article
Subject	Neuroscience

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