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Perinatal outcomes after previable preterm premature rupture of membranes before 24 weeks of gestation
| Content Provider | Scilit |
|---|---|
| Author | Kiver, Verena Boos, Vinzenz Thomas, Anke Henrich, Wolfgang Weichert, Alexander |
| Copyright Year | 2017 |
| Abstract | Objective: A current descriptive assessment of perinatal outcomes in pregnancies complicated by previable preterm premature rupture of membranes (pPPROM) at Study design: Maternal and short-term neonatal data were collected for patients with pPPROM. Results: Seventy-three patients with 93 fetuses were hospitalized with pPPROM at 15–24 weeks’ gestation. Among these patients, 27.4% (n=20) chose pregnancy termination, 27.4% (n=20) miscarried and 45.2% (n=33) proceeded to live births. After a median latency period of 38 days, ranging from 1 to 126 days, 24 singletons and 20 multiples were live-born, of whom 79.5% (n=35) survived the perinatal period. The main neonatal sequelae were pulmonary hypoplasia (29.5%; n=13), connatal infection (56.8%; n=25), intraventricular hemorrhage (25%; n=11; resulting in five neonatal deaths) and Potter’s syndrome (15.9%; n=7). Nine newborns died, within an average of 2.8 days (range, 1–10 days). The overall neonatal survival rate was 51.5% – including miscarriages but not elective terminations. The intact survival rate was 45.5% of all live-born neonates. Conclusions: Even with limited treatment options, overall neonatal survival is increasing. However, neonatal mortality and morbidity rates remain high. The gestational age at membrane rupture does not predict neonatal outcome. |
| Related Links | http://www.degruyter.com/downloadpdf/j/jpme.ahead-of-print/jpm-2016-0341/jpm-2016-0341.xml |
| Ending Page | 565 |
| Page Count | 11 |
| Starting Page | 555 |
| ISSN | 16193997 |
| e-ISSN | 03005577 |
| DOI | 10.1515/jpm-2016-0341 |
| Journal | Journal of Perinatal Medicine |
| Issue Number | 5 |
| Volume Number | 46 |
| Language | English |
| Publisher | Walter de Gruyter GmbH |
| Publisher Date | 2018-07-26 |
| Access Restriction | Open |
| Subject Keyword | Journal of Perinatal Medicine Obstetrics and Gynecology Pediatrics and Child Health Anhydramnios Hypoplasia Intraamniotic Infection Preterm Previable Prom Pulmonary Journal: Journal of Perinatal Medicine, Issue- 3 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pediatrics, Perinatology and Child Health Obstetrics and Gynecology |
