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Robust physiological control of rotary blood pumps for heart failure therapy
| Content Provider | Scilit |
|---|---|
| Author | Rüschen, Daniel Opitz, Sebastian von Platen, Philip Korn, Leonie Leonhardt, Steffen Walter, Marian |
| Copyright Year | 2018 |
| Abstract | Left ventricular assist devices (LVADs) have become a viable alternative to heart transplantation in heart failure therapy. In clinical practice, rotary blood pumps used as LVADs are operated at a constant rotational speed and thus do not adapt to the varying demand of the patient. This paper presents a robust control approach for automatic adaptation of the blood pump speed to the blood flow demand of the patient’s body, which enables a defined load sharing between an LVAD and the native ventricle. Robust stability was checked using a detailed model of the human cardiovascular system with uncertainties that describe the most important native physiological control loops as well as a range of pathologies. The robust assistance controller was tested in an in vivo setup and was able to stabilize the cardiovascular system after myocardial infarction. |
| Related Links | http://www.degruyter.com/downloadpdf/j/auto.2018.66.issue-9/auto-2018-0014/auto-2018-0014.xml |
| Ending Page | 779 |
| Page Count | 13 |
| Starting Page | 767 |
| ISSN | 01782312 |
| e-ISSN | 2196677X |
| DOI | 10.1515/auto-2018-0014 |
| Journal | at – Automatisierungstechnik |
| Issue Number | 9 |
| Volume Number | 66 |
| Language | English |
| Publisher | Walter de Gruyter GmbH |
| Publisher Date | 2018-09-25 |
| Access Restriction | Open |
| Subject Keyword | At – Automatisierungstechnik Biophysics Cardiovascular System Models Left Ventricular Assist Devices Physiological Control Robust Control Rotary Blood Pumps Journal: at – Automatisierungstechnik, Vol- 66 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Control and Systems Engineering Electrical and Electronic Engineering Computer Science Applications |
