Loading...
Please wait, while we are loading the content...
Similar Documents
Chlamydia pneumoniae infection in patients with chronic obstructive pulmonary disease
| Content Provider | Scilit |
|---|---|
| Author | Hertzen, L. V. O. N. Alakärppä, H. Koskinen, R. Liippo, K. Surcel, H. -M. Leinonen, M. Saikku, P. |
| Copyright Year | 1997 |
| Description | The prevalence of chronic Chlamydia pneumoniae infection was assessed in 54 patients with established chronic obstructive pulmonary disease (COPD), 41 of these with severe COPD (group I), 13 with mild to moderate COPD (group II), and in 23 patients with community-acquired pneumonia (controls, group III). Specific IgG and IgA antibody levels and circulating immune complexes (ICs) were measured in paired sera, and specific secretory IgA (sIgA) levels in sputum specimens. A polymerase chain reaction (PCR) test was used for the detection of C. pneumoniae in sputum. According to our definite diagnosis criterion, 65% of the COPD patients showed evidence of suspected chronic C. pneumoniae infection and the prevalence was still higher (71%) in patients with severe disease. The occurrence of specific markers of infection was invariably highest in patients with severe COPD, next-highest in patients with mild to moderate COPD and lowest in pneumonia patients. The association between COPD and C. pneumoniae infection persisted after controlling for the potential confounding factors. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808789/pdf https://www.cambridge.org/core/services/aop-cambridge-core/content/view/63A2929AD6919E0E8B509326A27A7352/S095026889600725Xa.pdf/div-class-title-span-class-italic-chlamydia-pneumoniae-span-infection-in-patients-with-chronic-obstructive-pulmonary-disease-div.pdf |
| Ending Page | 164 |
| Page Count | 10 |
| Starting Page | 155 |
| ISSN | 09502688 |
| e-ISSN | 14694409 |
| DOI | 10.1017/s095026889600725x |
| Journal | Epidemiology and Infection |
| Issue Number | 2 |
| Volume Number | 118 |
| Language | English |
| Publisher | Cambridge University Press (CUP) |
| Publisher Date | 1997-04-01 |
| Access Restriction | Open |
| Subject Keyword | Epidemiology and Infection Respiratory System Chlamydia Pneumoniae |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Epidemiology |
