Loading...
Please wait, while we are loading the content...
Similar Documents
Ileal digestibility of dietary protein in the growing pig and adult human
| Content Provider | Scilit |
|---|---|
| Author | Deglaire, Amélie Bos, Cécile Tomé, Daniel Moughan, Paul J. |
| Copyright Year | 2009 |
| Description | The suitability of the pig as an animal model for predicting protein digestibility in man was evaluated. Healthy adult human subjects (mean body weight 67 kg;n11) and growing pigs (mean body weight 40 kg;n15) were fed semi-synthetic mixed meals containing, as a sole source of N, casein (C), hydrolysed casein (HC) or rapeseed isolate (R). There was no prior adaptation to the test meal. Ileal digesta were sampled through a naso-ileal tube (human subjects) or a post-valve T-caecum cannula (pigs) after ingestion of a bolus meal. The protein sources $were^{15}$N-labelled. Amino acid (AA) digestibilities were not determined for R. Ileal apparent N digestibility was markedly lower (14–16 %;P < 0·001) in human subjects than in pigs (C, HC, R). Similarly, most apparent ileal AA digestibilities were lower (8 % on average;P < 0·05) in human subjects (C, HC). Ileal true N digestibility was slightly lower (3–5 %;P < 0·001) in human subjects than in pigs (C, HC, R) and most true ileal AA digestibilities were similar (P>0·05) between the species (C, HC). Exceptions were for phenylalanine, tyrosine, lysine, histidine and aspartic acid for which digestibilities were lower (3 % on average;P < 0·001) in human subjects. A similar ranking of the diets was observed for true ileal N digestibility between species. The inter-species correlation for true ileal digestibility was high for N (r0·98 over 3 × 2 data;P = 0·11) and AA (r0·87 over 26 × 2 data;P < 0·0001). Overall, this supports the use of the pig as a model for predicting differences among dietary protein digestibility, especially regarding true ileal N digestibility, in man. |
| Related Links | https://www.cambridge.org/core/services/aop-cambridge-core/content/view/E9A41CA323BD0A50ACB3567CBC269C5B/S0007114509991267a.pdf/div-class-title-ileal-digestibility-of-dietary-protein-in-the-growing-pig-and-adult-human-div.pdf |
| Ending Page | 1759 |
| Page Count | 8 |
| Starting Page | 1752 |
| ISSN | 00071145 |
| e-ISSN | 14752662 |
| DOI | 10.1017/s0007114509991267 |
| Journal | British Journal Of Nutrition |
| Issue Number | 12 |
| Volume Number | 102 |
| Language | English |
| Publisher | Cambridge University Press (CUP) |
| Publisher Date | 2009-12-28 |
| Access Restriction | Open |
| Subject Keyword | British Journal Of Nutrition Agriculture and Animal Production Ileal Digestibility |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nutrition and Dietetics Medicine |
