Biofilm accumulation on endotracheal tubes following prolonged intubation

Content Provider	Scilit
Author	Lee, J. M. Hashmi, N. Bloom, J. D. Tamashiro, E. Doghramji, L. Sarani, B. Palmer, J. N. Cohen, N. A. Mirza, N.
Copyright Year	2011
Description	Objective: To demonstrate that patients who have been intubated for prolonged periods of time will have an increased likelihood of developing bacterial biofilm on their endotracheal tubes.Methods: We collected endotracheal tubes from patients at the time of extubation, and analysed representative sections with scanning electron microscopy for morphologic evidence of biofilms.Results: From September 2007 to September 2008, 32 endotracheal tubes were analysed with electron microscopy. Patients who had been intubated for 6 days or longer had a significantly higher percentage of endotracheal tubes that exhibited bacterial biofilms, compared with patients intubated for less than 6 days (88.9 versus 57.1 per cent,p = 0.0439).Conclusions: Longer duration of intubation is associated with a higher incidence of bacterial biofilm. Further research is needed to link the presence of bacterial biofilms to acquired laryngotracheal damage.
Related Links	https://www.cambridge.org/core/services/aop-cambridge-core/content/view/B795E90B84D6FC95298A5261C5853566/S0022215111002969a.pdf/div-class-title-biofilm-accumulation-on-endotracheal-tubes-following-prolonged-intubation-div.pdf
Ending Page	270
Page Count	4
Starting Page	267
ISSN	00222151
e-ISSN	17485460
DOI	10.1017/s0022215111002969
Journal	The Journal of Laryngology & Otology
Issue Number	3
Volume Number	126
Language	English
Publisher	Cambridge University Press (CUP)
Publisher Date	2012-03-01
Access Restriction	Open
Subject Keyword	The Journal of Laryngology & Otology Tracheal Stenosis
Content Type	Text
Resource Type	Article
Subject	Otorhinolaryngology