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The impact of breast size on mean lung dose for patients receiving tangential radiotherapy to the whole breast
| Content Provider | Scilit |
|---|---|
| Author | Schembri, Ashley Mercieca, Susan Courtier, Nick Zarb, Francis |
| Copyright Year | 2016 |
| Description | Purpose: To explore the impact of breast size on mean lung dose (MLD) for patients receiving breast radiotherapy.Methodology: Chest wall separation (CWS), volume of tissue receiving 95% isodose and MLD were measured on 80 radiotherapy treatment plans of patients receiving tangential radiotherapy treatment to the whole breast. Breast size was categorised as small (CWS<25 cm and planned target volume (PTV)25 cm and PTV>1500 $cm^{3}$). Pearson’s correlation and independent sample t-test were used to analyse data.Results: MLD was not affected by CWS (r=−0·13, p=0·24) nor volume of tissue receiving 95% isodose (r=−0·08, p=0·49). Significant variation between small and large breasts was noted for CWS (t=8·24, p=0·00) and volume of tissue receiving 95% isodose (t=5·68, p=0·00). No significant variation was noted between small and large breast for MLD (t=−0·26, p=0·80) and between left and right breasts for CWS (t=1·42, p=0·16) and volume of tissue receiving 95% isodose (t=−1·08, p=0·28). Significant difference between left (18–808 cGy) and right breast (325–365 cGy) was demonstrated for MLD (t=3·03, p=0·00).Conclusion: This study demonstrated lack of correlation between breast size and MLD. Further research is recommended for justification of alternative techniques for this subgroup of patients to provide optimised radiotherapy delivery. |
| Related Links | https://www.cambridge.org/core/services/aop-cambridge-core/content/view/6E27728F113B65CA35E962C024B5B66C/S1460396916000091a.pdf/div-class-title-the-impact-of-breast-size-on-mean-lung-dose-for-patients-receiving-tangential-radiotherapy-to-the-whole-breast-div.pdf |
| Ending Page | 188 |
| Page Count | 8 |
| Starting Page | 181 |
| ISSN | 14603969 |
| e-ISSN | 14671131 |
| DOI | 10.1017/s1460396916000091 |
| Journal | Journal of Radiotherapy in Practice |
| Issue Number | 2 |
| Volume Number | 15 |
| Language | English |
| Publisher | Cambridge University Press (CUP) |
| Publisher Date | 2016-06-01 |
| Access Restriction | Open |
| Subject Keyword | Journal of Radiotherapy in Practice Respiratory System Breast Size Mean Lung Dose Tangential Whole Breast Radiotherapy |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging Oncology |
