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Under-recognized pertussis in adults from Asian countries: a cross-sectional seroprevalence study in Malaysia, Taiwan and Thailand
| Content Provider | Scilit |
|---|---|
| Author | Koh, M. T. Liu, C. -S. Chiu, C. -H. Boonsawat, W. Watanaveeradej, V. Abdullah, N. Zhang, Xh. Devadiga, R. Chen, J. |
| Copyright Year | 2015 |
| Description | SUMMARY: Surveillance data on the burden of pertussis in Asian adults are limited. This cross-sectional study evaluated the prevalence of serologically confirmed pertussis in adults with prolonged cough in Malaysia, Taiwan and Thailand. Adults (⩾19 years) with cough lasting for ⩾14 days without other known underlying cause were enrolled from outpatient clinics of seven public and/or private hospitals. Single blood samples for anti-pertussis toxin antibodies (anti-PT IgG) were analysed and economic impact and health-related quality of life (EQ-5D) questionnaires assessed. Sixteen (5·13%) of the 312 chronically coughing adults had serological evidence of pertussis infection within the previous 12 months (anti-PT IgG titre ⩾62·5 IU/ml). Three of them were teachers. Longer duration of cough, paroxysms (75% seroconfirmed, 48% non-seroconfirmed) and breathlessness/chest pain (63% seroconfirmed, 36% non-seroconfirmed) were associated with pertussis (P< 0·04). Of the seroconfirmed patients, the median total direct medical cost per pertussis episode in public hospitals (including physician consultations and/or emergency room visits) was US$13 in Malaysia, US$83 in Taiwan (n= 1) and US$26 in Thailand. The overall median EQ-5D index score of cases was 0·72 (range 0·42–1·00). Pertussis should be considered in the aetiology of adults with a prolonged or paroxysmal cough, and vaccination programmes considered. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825214/pdf https://www.cambridge.org/core/services/aop-cambridge-core/content/view/79EE41FFB29A304FA6D6977625EA9147/S0950268815002393a.pdf/div-class-title-under-recognized-pertussis-in-adults-from-asian-countries-a-cross-sectional-seroprevalence-study-in-malaysia-taiwan-and-thailand-div.pdf |
| Ending Page | 1200 |
| Page Count | 9 |
| Starting Page | 1192 |
| ISSN | 09502688 |
| e-ISSN | 14694409 |
| DOI | 10.1017/s0950268815002393 |
| Journal | Epidemiology and Infection |
| Issue Number | 6 |
| Volume Number | 144 |
| Language | English |
| Publisher | Cambridge University Press (CUP) |
| Publisher Date | 2015-10-15 |
| Access Restriction | Open |
| Subject Keyword | Epidemiology and Infection Respiratory System Bordetella Pertussis Infectious Disease Epidemiology Pertussis (whooping Cough) |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Epidemiology |
