A method for measuring the retained dose in experiments on airborne infection

Content Provider	Scilit
Author	Harper, G. J. Morton, J. D.
Copyright Year	1962
Description	When killed radioactive bacterial spores are inhaled by guinea-pigs and retained in the lung, it is found that the rate of loss up to 5 weeks later is sufficiently constant for the initial retention of a group of animals to be calculated from the measured retention at a later time (say 3 weeks after exposure). If, therefore, the inhaled cloud contained also a pathogen, in known proportion to the spores, the initial retention of the pathogen could be calculated. The experiments apply to groups of animals, but it is believed that the conclusions are valid also for single animals. In experiments withBr. suisit was found that the fate, as regards infection, of individual animals within a group exposed to a common dosage was not significantly related to the estimated retained dose, despite the wide variation of individual doses about the group mean.
Related Links	http://europepmc.org/articles/pmc2134408?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134408/pdf https://www.cambridge.org/core/services/aop-cambridge-core/content/view/B1AAD21A71ACB3EC7E52E9AE10E1C964/S0022172400039504a.pdf/div-class-title-a-method-for-measuring-the-retained-dose-in-experiments-on-airborne-infection-div.pdf
Ending Page	257
Page Count	9
Starting Page	249
ISSN	09502688
e-ISSN	14694409
DOI	10.1017/s0022172400039504
Journal	Epidemiology and Infection
Issue Number	2
Volume Number	60
Language	English
Publisher	Cambridge University Press (CUP)
Publisher Date	1962-06-01
Access Restriction	Open
Subject Keyword	Epidemiology and Infection Veterinary Sciences infection experimental
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Epidemiology