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Concentration of 25-hydroxyvitamin D from neonatal dried blood spots and the relation to gestational age, birth weight and Ponderal Index: the D-tect study
| Content Provider | Scilit |
|---|---|
| Author | Keller, Amélie Händel, Mina N. Frederiksen, Peder Jacobsen, Ramune Cohen, Arieh S. McGrath, John J. Heitmann, Berit L. |
| Copyright Year | 2018 |
| Description | Studies have suggested that vitamin D status at birth may be associated with a range of neonatal outcomes. The aim of this study was to assess the association between neonatal 25-hydroxyvitamin $D_{3}(25(OH)D_{3}$) concentration and gestational age, birth weight, Ponderal Index and size for gestational age. Neonatal capillary blood stored as dried blood spots was used to assess $25(OH)D_{3}$concentrations among 2686 subjects selected from a random population sub-sample of individuals, born in Denmark from 1 May 1981 to 31 December 2002. There was an inverse association between $25(OH)D_{3}$concentration and gestational age at birth of −0·006 (95 % CI −0·009, −0·003,P<0·001) weeks of gestation per 1 nmol/l increase in $25(OH)D_{3}$concentration. An inverted U-shaped association between $25(OH)D_{3}$and birth weight and Ponderal Index (P=0·04) was found, but no association with size for gestational age was shown. This study suggests that neonatal $25(OH)D_{3}$concentration is associated with anthropometric measures at birth known to be correlated with many subsequent health outcomes such as obesity and type 2 diabetes. |
| Related Links | https://www.cambridge.org/core/services/aop-cambridge-core/content/view/2A450A120E09330C7C50E1B36CE66A57/S0007114518000879a.pdf/div-class-title-concentration-of-25-hydroxyvitamin-d-from-neonatal-dried-blood-spots-and-the-relation-to-gestational-age-birth-weight-and-ponderal-index-the-d-tect-study-div.pdf |
| Ending Page | 1423 |
| Page Count | 8 |
| Starting Page | 1416 |
| ISSN | 00071145 |
| e-ISSN | 14752662 |
| DOI | 10.1017/s0007114518000879 |
| Journal | British Journal Of Nutrition |
| Issue Number | 12 |
| Volume Number | 119 |
| Language | English |
| Publisher | Cambridge University Press (CUP) |
| Publisher Date | 2018-04-25 |
| Access Restriction | Open |
| Subject Keyword | British Journal Of Nutrition Nutrition and Dietetics Dried Blood Spots Neonatal Outcomes hydroxyvitamin D Danish Medical Birth Register Large for Gestational Age Small for Gestational Age |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nutrition and Dietetics Medicine |
