NDLI: Antinuclear antibodies in suspected Systemic lupus erythematosus (SLE) patients of a tertiary care hospital- a retrospective study

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Antinuclear antibodies in suspected Systemic lupus erythematosus (SLE) patients of a tertiary care hospital- a retrospective study

Content Provider	Scilit
Author	Patil, Asha Kamath, Deepa Bairy, Indira Nayak, Kusumakshi Chaitra
Copyright Year	2022
Description	Background: In a systemic autoimmune disorder, non-organ-specific autoantibodies binding to the antigens are expressed within the human cells. The presence of antinuclear antibody (ANA) in the blood indicate an autoimmune disease. Objective: The study aims to estimate the frequency and prevalence of ANA in suspected autoimmune disorders in a tertiary care hospital. Materials and methods: A retrospective study and the ANA test results data obtained from the Laboratory Information System and laboratory records. Result: The frequency of the ANA test in six months was 5879; among them, 1638 (27.8 %) had ANA positive test either global or profile with female predominance (2:1). ANA positive test selected for further analysis was 401, in which 154(38%) were from the age group of 20 to 40 years. Conclusion: The estimated prevalence of ANA positive tests was 27.8%, which differed in different sex and age groups. In autoimmune conditions, estimating the prevalence of ANAs influences the trends of antinuclear antibodies. The test frequency and its interpretation assist in patient diagnosis and management, along with specific diagnostic tests. Bangladesh Journal of Medical Science Vol. 21 No. 02 April'22 Page : 279-283
Ending Page	283
Page Count	5
Starting Page	279
ISSN	22234721
e-ISSN	20760299
DOI	10.3329/bjms.v21i2.58059
Journal	Bangladesh Journal of Medical Science
Issue Number	2
Volume Number	21
Language	English
Publisher	Bangladesh Academy of Sciences
Publisher Date	2022-02-25
Access Restriction	Open
Subject Keyword	Antinuclear Antibodies
Content Type	Text
Resource Type	Article
Subject	Medicine

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