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Association between Serum C-reactive Protein and Pre-eclampsia
| Content Provider | Scilit |
|---|---|
| Author | Das, Sanjoy Kumar Khanam, Shafeya Roy, Rajib Kumar Alam, Samiya Roy, Tapan Kumar Joy, Swapna Biswas |
| Copyright Year | 2021 |
| Description | Among the common disorders of pregnancy, Pre-eclampsia is important one which causes significant maternal and perinatal morbidity and mortality. Its incidence is still high in the developing countries. The triad of high blood pressure, edema and albuminuria is neither specific nor sensitive enough; therefore, a reliable biochemical marker is needed to solve the problem. C-reactive protein(CRP), a marker of tissue damage and inflammation, is elevated in serum in overt preeclampsia. The present study is aimed to explore the association of high maternal serum C-reactive protein (CRP) level with preeclampsia and correlation with the severity of pre-eclamptic process. A total of 60 pregnant women constituting 30 pre-eclamptic (case) and 30 normal (control) pregnant women in the third trimester were enrolled in this study. Both the groups were matched for their age, parity and other baseline characteristics. More than three quarters (76.70%) of the case group exhibited raised serum CRP, which was 20% in control group (p=0.001). CRP was elevated about 13 fold higher than that in the normal pregnant women. The mean systolic and diastolic blood pressure were significantly higher in case group (154±12 mm of Hg) vs (107±7 mm of Hg) in control group (p<_0.001) and serum level of CRP bears linear relationship with both systolic and diastolic blood pressures. Preeclamptic women with higher serum CRP level were at a significantly (p<0.001) lower gestational age than control. Twenty two (73.30%) cases had gestational age 37 weeks. The hypothesis of the study was supported by the study findings that maternal CRP concentration was higher in women with preeclampsia and was correlated with disease progression as evidenced by the investigative analysis. Faridpur Med. Coll. J. Jan 2020;15(2): 58-61 |
| Ending Page | 61 |
| Page Count | 4 |
| Starting Page | 58 |
| ISSN | 20793553 |
| DOI | 10.3329/fmcj.v15i2.53888 |
| Journal | Faridpur Medical College Journal |
| Issue Number | 2 |
| Volume Number | 15 |
| Language | English |
| Publisher | Bangladesh Academy of Sciences |
| Publisher Date | 2021-06-08 |
| Access Restriction | Open |
| Subject Keyword | Obstetrics and Gynecology Blood Pressure Pregnant Women |
| Content Type | Text |
| Resource Type | Article |
