NDLI: Detection of drug-resistant Mycobacterium tuberculosis from TB suspected diabetic patients by GeneXpert MTB/RIF method

Please wait, while we are loading the content...

Detection of drug-resistant Mycobacterium tuberculosis from TB suspected diabetic patients by GeneXpert MTB/RIF method

Content Provider	Scilit
Author	Husna, Asmaul Dhar, Tushar Kanti Munshi, Saurab Kishore
Copyright Year	2015
Description	Multidrug-resistant tuberculosis (MDR-TB) has become one of the major public health menace in the developing countries which have destructive consequences in immunocompromised patients. Rapid detection of such cases is indispensable to initiate the early and proper treatment of the infected individuals. Present study was conducted to determine the frequency of drug resistant Mycobacterium tuberculosis among the TB suspected diabetic patients employing GeneXpert MTB/RIF method. A total of 1311 sputum specimens were tested among which 154 (11.7%), 109 (8.3%) and 92 (7%) were found to carry Mycobacterium tuberculosis by GeneXpert, auramine O staining and Zeihl-Neelsen (Z-N) staining methods, consecutively. The relative positivity of the GeneXpert method was 40.3% and 29.2% higher than that of Z-N and auramine O staining methods. The sensitivity, specificity and accuracy of GeneXpert method were found to be higher when compared to these microscopic techniques. An estimation of 12.9% (n=132) of the positive cases was found among the diabetic patients (n=1027), whereas 7.7% (n=22) of the non-diabetic patients (n=284) showed positivity by GeneXpert method. Four (2.6%) among the MTB positive cases exhibited rifampicin resistance of which 3 were diabetic patients. DOI: http://dx.doi.org/10.3329/sjm.v4i1.22754 Stamford Journal of Microbiology, Vol.4(1) 2014: 9-12
ISSN	20745346
e-ISSN	24088846
DOI	10.3329/sjm.v4i1.22754
Journal	Stamford Journal of Microbiology
Issue Number	1
Volume Number	4
Language	English
Publisher	Bangladesh Academy of Sciences
Publisher Date	2015-03-27
Access Restriction	Open
Subject Keyword	Diabetes Mellitus
Content Type	Text
Resource Type	Article

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in