NDLI: Fatty acid analysis, cytotoxicity, antimicrobial and antioxidant activities of different extracts of the flowers of Nyctanthes arbor-tristis L.

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Fatty acid analysis, cytotoxicity, antimicrobial and antioxidant activities of different extracts of the flowers of Nyctanthes arbor-tristis L.

Content Provider	Scilit
Author	Haque, Mm Sultana, N Abedin, Smt Hossain, N Kabir, Se
Copyright Year	2020
Description	The fatty acid analysis and biological activity of n-hexane, dichloromethane, ethyl acetate and methanol extracts of Nyctanthes arbor-tristis L. flowers are reported. Five fatty acids namely palmitic (44.15%), stearic (19.34%), arachidic (15.06%), behenic (9.77%) and lignoceric (11.69%) acids were identified. From cytotoxicity test, the LC50 values (the median lethal concentration) for n-hexane, dichloromethane, ethyl acetate and methanol extracts as well as for standard vincristine sulphate were found 7.05, 4.67, 3.14, 5.53 and 0.50 μg/ml, respectively. Antibacterial activity results of different extracts were compared with standard antibiotic ciprofloxacin and tetracycline by measuring the zone of inhibition diameter in millimeter. The dichloromethane and ethyl acetate extracts showed significant antibacterial activity. From antioxidant activity test, IC50 values (50% inhibitory concentration) of n-hexane, dichloromethane, ethyl acetate, methanol extracts and ascorbic acid were found to be 291.92 mg/ml, 45.74 μg/ml, 21.86 μg/ml, 64.30 μg/ml and 3.98 μg/ml, respectively. Bangladesh J. Sci. Ind. Res.55(3), 207-214, 2020
Ending Page	214
Page Count	8
Starting Page	207
ISSN	03049809
e-ISSN	22247157
DOI	10.3329/bjsir.v55i3.49394
Journal	Bangladesh Journal of Scientific and Industrial Research
Issue Number	3
Volume Number	55
Language	English
Publisher	Bangladesh Academy of Sciences
Publisher Date	2020-09-24
Access Restriction	Open
Subject Keyword	Integrative and Complementary Medicine Antioxidant Activities Ethyl Acetate Methanol Extracts
Content Type	Text
Resource Type	Article

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