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Potential impact of complement regulator deficiencies on hemolytic reactions due to minor ABO-mismatched transfusions
| Content Provider | Scilit |
|---|---|
| Author | Pandey, Priyanka Anani, Waseem Q. Gottschall, Jerome L. Denomme, Gregory A. |
| Copyright Year | 2017 |
| Description | Key Points An in vitro model shows that hemolysis could be due to the presence of a subclinical PNH clone causing a negative C3b/d DAT. Changes to decay-accelerating factor and membrane inhibitor of reactive lysis may lead to overt hemolysis after minor mismatched transfusions. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728284/pdf |
| Ending Page | 1982 |
| Page Count | 6 |
| Starting Page | 1977 |
| DOI | 10.1182/bloodadvances.2017008805 |
| Journal | Blood advances |
| Issue Number | 23 |
| Volume Number | 1 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2017-10-11 |
| Access Restriction | Open |
| Subject Keyword | Anesthesiology Igm Incubation Infrequent Transfusion of Minor Abo Minor Abo Mismatched Transfusions Journal: Blood advances (Vol- 136, Issue- 23) |
| Content Type | Text |
| Resource Type | Article |