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BAVC regimen and autologous bone marrow transplantation in patients with acute myelogenous leukemia in second remission
| Content Provider | Scilit |
|---|---|
| Author | Meloni, G. Fabritiis, P. De Petti, Mc Mandelli, F. |
| Copyright Year | 1990 |
| Description | Twenty-one acute myelogenous leukemia (AML) patients were submitted in second remission (II CR) to BAVC conditioning regimen followed by unpurged ABMT. Transplant was done after a median of 2 months from II CR (range, 1 to 13). Median first remission (I CR) duration was 16 months (range, 1–35). Conditioning regimen was well tolerated, with no major extra-medullary toxicity. One patient died during aplasia from fungal sepsis. Of the 20 evaluable patients, nine relapsed after a median time of 6 months (range, 2 to 18). Eleven patients are in continuous complete remission (CCR) after a median follow-up of 40 months (range, 24 to 63). The duration of II CR has exceeded the duration of I CR in all patients in CCR. Projected probability of disease-free survival is 52% at 63 months. |
| Related Links | https://ashpublications.org/blood/article-pdf/75/12/2282/210373/2282.pdf |
| Ending Page | 2285 |
| Page Count | 4 |
| Starting Page | 2282 |
| DOI | 10.1182/blood.v75.12.2282.bloodjournal75122282 |
| Journal | Blood |
| Issue Number | 12 |
| Volume Number | 75 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 1990-06-15 |
| Access Restriction | Open |
| Subject Keyword | Hematology Survival Bone Marrow Leukemia Remission Duration Ccr Tolerated Myelogenous Bavc Journal: Blood (Vol- 118, Issue- 12) |
| Content Type | Text |
| Resource Type | Article |
