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Platelet CD36 promotes thrombosis by activating redox sensor ERK5 in hyperlipidemic conditions
| Content Provider | Scilit |
|---|---|
| Author | Yang, Moua Cooley, Brian C. Li, Wei Chen, Yiliang Vasquez-Vivar, Jeannette Scoggins, Na’Il O. Cameron, Scott J. Morrell, Craig N. Silverstein, Roy L. |
| Copyright Year | 2017 |
| Description | Key Points: Atherogenic conditions promote platelet CD36 signaling by generating specific reactive oxygen species. Redox sensor ERK5 MAP kinase activation by reactive oxygen species potentiates thrombus formation in hyperlipidemic conditions. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445574/pdf |
| Ending Page | 2927 |
| Page Count | 11 |
| Starting Page | 2917 |
| DOI | 10.1182/blood-2016-11-750133 |
| Journal | Blood |
| Issue Number | 21 |
| Volume Number | 129 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2017-05-25 |
| Access Restriction | Open |
| Subject Keyword | Kinase Thrombus Thrombosis Atherogenic Platelet Cd36 Redox Hyperlipidemic Oxygen Journal: Blood (Vol- 134, Issue- 21) |
| Content Type | Text |
| Resource Type | Article |