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Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms
| Content Provider | Scilit |
|---|---|
| Author | Lykken, Jacquelyn M. Horikawa, Mayuka Minard-Colin, Veronique Kamata, Masahiro Miyagaki, Tomomitsu Poe, Jonathan C. Tedder, Thomas F. |
| Copyright Year | 2016 |
| Description | Key Points A preclinical model system was developed to define the molecular landscape dictating lymphoma resistance to immunotherapy. This system revealed that Gal-1 significantly inhibits CD20 immunotherapy within the lymphoma microenvironment in vivo. |
| Related Links | https://ashpublications.org/blood/article-pdf/127/15/1886/1392767/1886.pdf |
| Ending Page | 1895 |
| Page Count | 10 |
| Starting Page | 1886 |
| DOI | 10.1182/blood-2015-11-681130 |
| Journal | Blood |
| Issue Number | 15 |
| Volume Number | 127 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2016-04-14 |
| Access Restriction | Open |
| Subject Keyword | Research and Experimental Medicine Model Dictating Galectin Resistance To Immunotherapy Cd20 Immunotherapy Within the Lymphoma Journal: Blood (Vol- 125, Issue- 15) |
| Content Type | Text |
| Resource Type | Article |