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miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1
| Content Provider | Scilit |
|---|---|
| Author | Mraz, Marek Chen, Liguang Rassenti, Laura Z. Ghia, Emanuela M. Li, Hongying Jepsen, Kristen Smith, Erin N. Messer, Karen Frazer, Kelly Kipps, Thomas J. |
| Copyright Year | 2014 |
| Description | Key Points The most abundant miRNA in CLL, miR-150, is expressed at lower levels in cases with unfavorable clinicobiological markers and worse prognosis. miR-150 regulates expression of genes encoding proteins that modulate BCR signaling in CLL. |
| Related Links | http://www.bloodjournal.org/content/bloodjournal/124/1/84.full.pdf |
| Ending Page | 95 |
| Page Count | 12 |
| Starting Page | 84 |
| DOI | 10.1182/blood-2013-09-527234 |
| Journal | Blood |
| Issue Number | 1 |
| Volume Number | 124 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2014-07-03 |
| Access Restriction | Open |
| Subject Keyword | Hematology Medical Laboratory Technology Prognosis Proteins Leukemia Bcr Gab1 Foxp1 Expression of Genes Abundant Worse Clinicobiological Journal: Blood (Vol- 22, Issue- 1) |
| Content Type | Text |
| Resource Type | Article |