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Granulocyte colony-stimulating factor "mobilized" peripheral blood progenitor cells accelerate granulocyte and platelet recovery after high-dose chemotherapy
| Content Provider | Scilit |
|---|---|
| Author | Chao, Nj Schriber, Jr Grimes, K. Long, Gd Negrin, Rs Raimondi, Cm Horning, Sj Brown, Sl Miller, L. Blume, Kg |
| Copyright Year | 1993 |
| Description | Hematopoietic growth factors have been used to accelerate engraftment after bone marrow transplantation and to “mobilize” peripheral blood progenitor cells (PBPC). We report on the data in 85 consecutive patients with Hodgkin's disease who were treated in a single institution using different methods to obtain PB progenitor cells. Use of granulocyte colony-stimulating factor for mobilization resulted in a significantly accelerated time to recovery of granulocytes (10 days v 12 days, P < .01) when compared with “nonmobilized” PBPC recipients. Similarly, use of mobilized PBPC resulted in a significantly accelerated time to platelet engraftment (13 days v 30 days, P < .001) when compared with “nonmobilized” recipients. Moreover, there was a statistically significant difference in total costs in favor of the group receiving “mobilized” PBPC. |
| Related Links | https://ashpublications.org/blood/article-pdf/81/8/2031/609202/2031.pdf |
| Ending Page | 2035 |
| Page Count | 5 |
| Starting Page | 2031 |
| DOI | 10.1182/blood.v81.8.2031.2031 |
| Journal | Blood |
| Issue Number | 8 |
| Volume Number | 81 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 1993-04-15 |
| Access Restriction | Open |
| Subject Keyword | Hematology Hematopoietic Bone Marrow Platelet Progenitor Cells Granulocyte Recipients Peripheral Accelerate Nonmobilized Journal: Blood (Vol- 102, Issue- 8) |
| Content Type | Text |
| Resource Type | Article |
