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Hairpin and allosteric regulation in ADAMTS13
| Content Provider | Scilit |
|---|---|
| Author | Chung, Dominic W. |
| Copyright Year | 2019 |
| Description | In this issue of Blood, Muia et $al^{1}$ and Zhu et $al,^{2}$ using complementary approaches, provide important insights into the structure and function of ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin-1 repeats, member 13), identifying critical structural features and interactions that allosterically regulate its proteolytic activity on von Willebrand factor (VWF). |
| Related Links | https://ashpublications.org/blood/article-pdf/133/17/1800/1557144/blood900563.pdf |
| Ending Page | 1801 |
| Page Count | 2 |
| Starting Page | 1800 |
| DOI | 10.1182/blood-2019-02-900563 |
| Journal | Blood |
| Issue Number | 17 |
| Volume Number | 133 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2019-04-25 |
| Access Restriction | Open |
| Subject Keyword | Hematology Function Adamts13 Von Willebrand Structural Features Proteolytic Activity Identifying Critical Important Insights Willebrand Factor Allosterically Regulate Journal: Blood (Vol- 128, Issue- 17) |
| Content Type | Text |
| Resource Type | Article |