Loading...
Please wait, while we are loading the content...
Similar Documents
Dichloroacetate, an inhibitor of pyruvate dehydrogenase kinases, inhibits platelet aggregation and arterial thrombosis
| Content Provider | Scilit |
|---|---|
| Author | Nayak, Manasa Dhanesha, Nirav Doddapattar, Prakash Rodriguez, Omar Sonkar, Vijay K. Dayal, Sanjana Chauhan, Anil K. |
| Copyright Year | 2018 |
| Description | Key Points DCA, an inhibitor of PDKs, impedes glucose uptake and aerobic glycolysis in activated platelets. DCA inhibits agonist-induced human and mouse platelet aggregation and arterial thrombosis without altering hemostasis in mice. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093723/pdf |
| Ending Page | 2038 |
| Page Count | 10 |
| Starting Page | 2029 |
| DOI | 10.1182/bloodadvances.2018022392 |
| Journal | Blood advances |
| Issue Number | 15 |
| Volume Number | 2 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2018-08-14 |
| Access Restriction | Open |
| Subject Keyword | Hematology Phosphorylation Platelets Platelet Aggregation Adenosine Platelet Function Pdk Artery Thrombosis Convulxin Journal: Blood advances (Vol- 124, Issue- 15) |
| Content Type | Text |
| Resource Type | Article |