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Tonic B-cell receptor signaling in diffuse large B-cell lymphoma
| Content Provider | Scilit |
|---|---|
| Author | Havranek, Ondrej Xu, Jingda Köhrer, Stefan Wang, Zhiqiang Becker, Lisa Comer, Justin M. Henderson, Jared Ma, Wencai Westin, Jason R. Ghosh, Dipanjan Shinners, Nicholas Sun, Luhong Yi, Allen F. Karri, Anusha R. Burger, Jan A. Zal, Tomasz Davis, R. Eric |
| Copyright Year | 2017 |
| Description | Key Points The GCB subtype of DLBCL relies exclusively on tonic BCR signaling via CD79A Y188. PTEN protein expression and BCR surface density determine the contribution of tonic BCR signaling to AKT activity in GCB-DLBCL. |
| Related Links | https://ashpublications.org/blood/article-pdf/130/8/995/1404876/blood747303.pdf |
| DOI | 10.1182/blood-2016-10-747303 |
| Journal | Blood |
| Issue Number | 8 |
| Volume Number | 130 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2017-08-24 |
| Access Restriction | Open |
| Subject Keyword | Hematology Gene Expression Protein Signaling Antigen Dlbcl Tonic Bcr Showed Bcr Inhibited Tonic Effect of Bcr Journal: Blood (Vol- 106, Issue- 8) |
| Content Type | Text |
| Resource Type | Article |