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Current treatment of double hit and double expressor lymphoma
| Content Provider | Scilit |
|---|---|
| Author | Reagan, Patrick M. Davies, Andrew |
| Copyright Year | 2017 |
| Description | A 60-year-old female presented with abdominal pain and distension. Following computed tomography scans of the abdomen and pelvis, she was taken urgently to the operating room, with the belief that she had appendicitis with perforation. At laparotomy, the findings were consistent with an ovarian carcinoma; there was extensive infiltration of the ovary, bowel, and omental deposits. Cytoreductive surgery was performed including total abdominal hysterectomy and bilateral salpingo-oophorectomy. The final pathology, however, revealed infiltration with medium-sized atypical lymphoid cells positive for CD20, CD10, MYC, BLC2, and BCL6 by immunohistochemistry. MYC and BCL2 translocations were identified by fluorescence in situ hybridization consistent with a diagnosis of high-grade B-cell lymphoma with rearrangements of MYC and BCL2. With the current data available, what is the optimal treatment of this patient? |
| Related Links | https://ashpublications.org/hematology/article-pdf/2017/1/295/1249964/hem00040.pdf |
| Ending Page | 297 |
| Page Count | 3 |
| Starting Page | 295 |
| DOI | 10.1182/asheducation-2017.1.295 |
| Journal | Hematology |
| Issue Number | 1 |
| Volume Number | 2017 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2017-12-08 |
| Access Restriction | Open |
| Subject Keyword | Hematology Infiltration Lymphoma Optimal Abdominal Treatment Double Hit Myc and Bcl2 Journal: Hematology (Vol- 36, Issue- 1) |
| Content Type | Text |
| Resource Type | Article |
