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Successful allogeneic engraftment of mismatched unrelated cord blood following a nonmyeloablative preparative regimen
| Content Provider | Scilit |
|---|---|
| Author | Rizzieri, David A. Long, Gwynn D. Vredenburgh, James J. Gasparetto, Christina Morris, Ashley Stenzel, Timothy T. Davis, Patti Chao, Nelson J. |
| Copyright Year | 2001 |
| Description | Reduction in the toxicity of allogeneic transplantation with nonmyeloablative induction regimens has expanded the scope of practice to older and more debilitated patients. However, the limited availability of matched sibling donors requires that alternative donor sources be investigated. Reported here are 2 cases of patients with advanced hematologic malignancies without matched siblings, partially matched family members, or matched unrelated donors who successfully underwent nonmyeloablative conditioning therapy followed by infusion of partially matched, unrelated-donor cord blood cells. The patients are in remission and remain 100% donor as assessed by short tandem repeat analysis of the marrow 6 and 12 months following transplantation. |
| Related Links | http://pdfs.semanticscholar.org/df5a/454981e20c92c7867c0d57981f133ee0fc16.pdf |
| Ending Page | 3488 |
| Page Count | 3 |
| Starting Page | 3486 |
| DOI | 10.1182/blood.v98.12.3486 |
| Journal | Blood |
| Issue Number | 12 |
| Volume Number | 98 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2001-12-01 |
| Access Restriction | Open |
| Subject Keyword | Hematology Transplantation Allogeneic Cord Blood Siblings Donor Nonmyeloablative Matched Partially Unrelated Journal: Blood (Vol- 120, Issue- 12) |
| Content Type | Text |
| Resource Type | Article |
