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WNT5A is epigenetically silenced in hematologic malignancies and inhibits leukemia cell growth as a tumor suppressor
| Content Provider | Scilit |
|---|---|
| Author | Ying, Jianming Li, Hongyu Chen, Yun-Wen Srivastava, Gopesh Gao, Zifen Tao, Qian |
| Copyright Year | 2007 |
| Description | To the editor: Aberrant activation of the Wnt/β-catenin signaling pathway is a hallmark of cancers.[1][1],[2][2] A recent Blood report showed the down-regulation of multiple Wnt-signaling inhibitors including SFRPs, WIF1 , DKK3 , and DACT1 in acute lymphoblastic leukemia (ALL) cell lines and |
| Related Links | http://www.bloodjournal.org/content/110/12/4130.full.pdf |
| Ending Page | 4131 |
| Page Count | 2 |
| Starting Page | 4130 |
| DOI | 10.1182/blood-2007-06-094870 |
| Journal | Blood |
| Issue Number | 12 |
| Volume Number | 110 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2007-12-01 |
| Access Restriction | Open |
| Subject Keyword | Hematology Hematologic Malignancies Tumor Suppressor Wnt5a Inhibits Leukemia Epigenetically Silenced Cell Growth Journal: Blood (Vol- 121, Issue- 12) |
| Content Type | Text |
| Resource Type | Article |