NDLI: Controversies in Treatment of AML: Case-based Discussion

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Controversies in Treatment of AML: Case-based Discussion

Content Provider	Scilit
Author	Stock, Wendy
Copyright Year	2006
Description	Treatment of acute myeloid leukemia (AML) in older adults remains a tremendous challenge. Standard approaches to treatment have resulted in progression-free survival in only a small minority of patients with AML over the age of 60. Elucidation of the molecular genetic events that contribute to the pathogenesis of AML in older patients are providing insights into mechanisms of resistance. This knowledge is also providing new opportunities to begin to refine and direct novel therapies for these heterogeneous diseases. In this case-based review, prognostic factors for treatment outcome in older adults will be covered along with discussion of a risk-based approach to potential therapeutic options, ranging from palliative care to novel therapies and reduced-intensity allogenenic transplant.
Related Links	http://asheducationbook.hematologylibrary.org/content/2006/1/185.full.pdf
Ending Page	191
Page Count	7
Starting Page	185
DOI	10.1182/asheducation-2006.1.185
Journal	Hematology
Issue Number	1
Volume Number	2006
Language	English
Publisher	American Society of Hematology
Publisher Date	2006-01-01
Access Restriction	Open
Subject Keyword	Gerontology Therapies Older Adults Aml Pathogenesis Palliative Care Acute Myeloid Leukemia Case Based Treatment Outcome Journal: Hematology (Vol- 27, Issue- 1)
Content Type	Text
Resource Type	Article

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