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Chromosome Studies in Normal and Leukemic Rats
| Content Provider | Scilit |
|---|---|
| Author | Dowd, G. Dunn, K. Moloney, William C. |
| Copyright Year | 1964 |
| Description | 1. Adequate chromosome preparations were obtained in 70 per cent of normal rat peripheral blood cell cultures. However, cultures of peripheral blood cells from leukemic rats were almost universally unsuccessful. 2. In x-ray- and 3MCA-induced leukemias direct bone marrow preparations provided adequate metaphases in eight of 12 cases. Failures were attributed in four cases to scanty material obtained from fibrotic marrows. 3. No consistent chromosome abnormalities, such as those reported in human myelogenous leukemia, were found in these leukemic rats. However, the series of cases is small, and species differences and other factors may have influenced the results of these studies. |
| Related Links | https://ashpublications.org/blood/article-pdf/23/5/564/571665/564.pdf |
| Ending Page | 571 |
| Page Count | 8 |
| Starting Page | 564 |
| DOI | 10.1182/blood.v23.5.564.564 |
| Journal | Blood |
| Issue Number | 5 |
| Volume Number | 23 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 1964-05-01 |
| Access Restriction | Open |
| Subject Keyword | Pathology Bone Marrow Cell Cultures Leukemia Peripheral Blood Chromosome Adequate Blood Cell Leukemic Rats Journal: Blood (Vol- 80, Issue- 5) |
| Content Type | Text |
| Resource Type | Article |
