NDLI: Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy

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Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy

Content Provider	Scilit
Author	O’Brien, Susan Woyach, Jennifer A. Smucker, Kelly Smith, Lisa L. Lozanski, Arletta Zhong, Yiming Ruppert, Amy S. Lucas, David Williams, Katie Zhao, Weiqiang Rassenti, Laura Ghia, Emanuela Kipps, Thomas J. Mantel, Rose Jones, Jeffrey Flynn, Joseph Maddocks, Kami Furman, Richard R. James, Danelle F. Clow, Fong Lozanski, Gerard Johnson, Amy J. Byrd, John C.
Copyright Year	2014
Description	Key Points Persistent CLL cells during ibrutinib therapy show evidence of biochemical activation, but inhibited BCR and no proliferation. Long lymphocytosis during ibrutinib therapy is not associated with adverse progression-free survival.
Related Links	http://www.bloodjournal.org/content/bloodjournal/123/12/1810.full.pdf
Ending Page	1817
Page Count	8
Starting Page	1810
DOI	10.1182/blood-2013-09-527853
Journal	Blood
Issue Number	12
Volume Number	123
Language	English
Publisher	American Society of Hematology
Publisher Date	2014-03-20
Access Restriction	Open
Subject Keyword	Research and Experimental Medicine Survival Cll Prolonged Therapy Is Associated Lymphocytosis During Ibrutinib Therapy Ibrutinib Therapy Is Not Associated Journal: Blood (Vol- 121, Issue- 12)
Content Type	Text
Resource Type	Article

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