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Chronic myelocytic leukemia: eosinophils involved in the malignant clone
| Content Provider | Scilit |
|---|---|
| Author | Koeffler, Hp Sparkes, M. Sparkes, Rs |
| Copyright Year | 1980 |
| Description | Chronic myelocytic leukemia (CML) is a clonal disorder involving neutrophil, monocyte, erythrocyte, and platelet precursors. In order to determine if the eosinophils are also involved in the leukemic clone, we purified the eosinophils from a woman heterozygous for the common electrophoretic variants of the G6PD gene. Only type B enzyme was demonstrable in the eosinophils, neutrophils, and red cells, but both A and B enzymes were found in the fibroblasts. The data provide evidence that the eosinophil is involved in the malignant clone. |
| Related Links | https://ashpublications.org/blood/article-pdf/55/6/1063/583771/1063.pdf |
| Ending Page | 1065 |
| Page Count | 3 |
| Starting Page | 1063 |
| DOI | 10.1182/blood.v55.6.1063.1063 |
| Journal | Blood |
| Issue Number | 6 |
| Volume Number | 55 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 1980-06-01 |
| Access Restriction | Open |
| Subject Keyword | Hematology Eosinophils Malignant Clone Erythrocyte Clonal Electrophoretic Leukemic Myelocytic Leukemia Journal: Blood (Vol- 86, Issue- 6) |
| Content Type | Text |
| Resource Type | Article |
