Current approaches to prevent and treat GVHD after allogeneic stem cell transplantation

Content Provider	Scilit
Author	Hamilton, Betty Ky
Copyright Year	2018
Description	Allogeneic hematopoietic cell transplantation is a potentially curative therapy for many malignant and nonmalignant hematologic diseases. Graft-versus-host disease (GVHD) is a common complication after transplantation and remains a major cause of morbidity and mortality, limiting the success of a potentially curative transplant. This paper reviews the current and emerging strategies in GVHD prevention and treatment. New insights are leading the way to the development of novel targeted approaches to minimize the risk of disease relapse and infection. Continued collaborative efforts to conduct high-quality, multicenter clinical trials with standard end points and risk stratification are needed to determine the optimal approach to minimize GVHD and limit toxicities.
Related Links	https://ashpublications.org/hematology/article-pdf/2018/1/228/1253389/hem01831.pdf
Ending Page	235
Page Count	8
Starting Page	228
DOI	10.1182/asheducation-2018.1.228
Journal	Hematology
Issue Number	1
Volume Number	2018
Language	English
Publisher	American Society of Hematology
Publisher Date	2018-11-30
Access Restriction	Open
Subject Keyword	Hematology Cell Transplantation Optimal Treatment Hematopoietic Minimize Gvhd Allogeneic Potentially Curative Journal: Hematology (Vol- 37, Issue- 1)
Content Type	Text
Resource Type	Article