Loading...
Please wait, while we are loading the content...
Similar Documents
Acute lymphoblastic leukemia with pre-B-cell characteristics
| Content Provider | Scilit |
|---|---|
| Author | Brouet, Jc Preud'homme, Jl Penit, C. Valensi, F. Rouget, P. Seligmann, M. |
| Copyright Year | 1979 |
| Description | Blast cells from 6 of 50 patients with acute lymphoblastic leukemia (ALL) displayed intracytoplasmic mu chains in the absence of detectable light chains and surface immunoglobulins. These cells also expressed lalike and common ALL antigens. Terminal deoxynucleotidyltransferase was detectable in 2 of 5 cases tested. These blast cells are probably related to early B-cell precursors (pre-B cells). In 4 of 6 cases the disease had a tumoral presentation; the prognostic significance of this new subgroup, which accounts for 20% of patients with non-T non-B ALL, remains to be established. |
| Related Links | https://ashpublications.org/blood/article-pdf/54/1/269/206731/269.pdf |
| Ending Page | 273 |
| Page Count | 5 |
| Starting Page | 269 |
| DOI | 10.1182/blood.v54.1.269.bloodjournal541269 |
| Journal | Blood |
| Issue Number | 1 |
| Volume Number | 54 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 1979-07-01 |
| Access Restriction | Open |
| Subject Keyword | Hematology Antigens Immunoglobulins Terminal Pre Lymphoblastic Leukemia Deoxynucleotidyltransferase Journal: Blood (Vol- 3, Issue- 1) |
| Content Type | Text |
| Resource Type | Article |