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Low factor V level ameliorates bleeding diathesis in patients with combined deficiency of factor V and factor VIII
| Content Provider | Scilit |
|---|---|
| Author | Shao, Yanyan Wu, Wenman Xu, Guanqun Wang, Xuefeng Ding, Qiulan |
| Copyright Year | 2019 |
| Description | Combined factor V and factor VIII deficiency is a rare disorder associated with relatively mild bleeding diathesis. Shao and colleagues elucidate the double role of factor V as both a pro- and anticoagulant protein, demonstrating that decreased factor V may ameliorate factor VIII deficiency through decreasing the level of tissue factor pathway inhibitor. |
| Related Links | http://www.bloodjournal.org/content/bloodjournal/early/2019/09/26/blood.2018886069.full.pdf |
| Ending Page | 1754 |
| Page Count | 10 |
| Starting Page | 1745 |
| DOI | 10.1182/blood.2018886069 |
| Journal | Blood |
| Issue Number | 20 |
| Volume Number | 134 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2019-09-26 |
| Access Restriction | Open |
| Subject Keyword | Hematology Protein Deficiency Bleeding Tissue Anticoagulant Double Diathesis Colleagues Shao Ameliorates Journal: Blood (Vol- 132, Issue- 20) |
| Content Type | Text |
| Resource Type | Article |
