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CD8+ T cells are predominantly protective and required for effective steroid therapy in murine models of immune thrombocytopenia
| Content Provider | Scilit |
|---|---|
| Author | Ma, Li Simpson, Elisa Li, June Xuan, Min Xu, Miao Baker, Laura Shi, Yan Yougbaré, Issaka Wang, Xiaozhong Zhu, Guangheng Chen, Pingguo Prud’Homme, Gerald J. Lazarus, Alan H. Freedman, John Ni, Heyu |
| Copyright Year | 2015 |
| Description | Key Points CD8+ T cells play a predominantly protective role in both passive and active murine models of ITP. CD8+ T-regulatory cells contribute to efficacious response to steroid therapy and may be important diagnostic/prognostic biomarkers for ITP. |
| Related Links | http://www.bloodjournal.org/content/bloodjournal/126/2/247.full.pdf |
| Ending Page | 256 |
| Page Count | 10 |
| Starting Page | 247 |
| DOI | 10.1182/blood-2015-03-635417 |
| Journal | Blood |
| Issue Number | 2 |
| Volume Number | 126 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2015-07-09 |
| Access Restriction | Open |
| Subject Keyword | Hematology Autoantibodies Tregs Therapy Steroid Cytotoxic Cd8 Immune Thrombocytopenia Immunosuppressive Platelet Journal: Blood (Vol- 61, Issue- 2) |
| Content Type | Text |
| Resource Type | Article |