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HSP90 inhibition without heat shock response
| Content Provider | Scilit |
|---|---|
| Author | Byrd, John C. |
| Copyright Year | 2018 |
| Description | In this issue of Blood, Bhatia and colleagues describe a heat shock protein 90 (HSP90) C-terminal dimerization inhibitor with mechanistic differences that distinguish it from other clinically unsuccessful N-terminal ATPase binding $compounds.^{1}$ Can graveyard raiding of an old therapeutic target with a new strategy bring long awaited success? |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053952/pdf |
| Ending Page | 242 |
| Page Count | 2 |
| Starting Page | 241 |
| DOI | 10.1182/blood-2018-05-850271 |
| Journal | Blood |
| Issue Number | 3 |
| Volume Number | 132 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2018-07-19 |
| Access Restriction | Open |
| Subject Keyword | Hematology Protein Heat Shock Atpase Hsp90 Old Colleagues Distinguish Bring Journal: Blood (Vol- 72, Issue- 3) |
| Content Type | Text |
| Resource Type | Article |