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Novel mechanisms of PIEZO1 dysfunction in hereditary xerocytosis
| Content Provider | Scilit |
|---|---|
| Author | Glogowska, Edyta Schneider, Eve R. Maksimova, Yelena Schulz, Vincent P. Lezon-Geyda, Kimberly Wu, John Radhakrishnan, Kottayam Keel, Siobán B. Mahoney, Donald Freidmann, Alison M. Altura, Rachel A. Gracheva, Elena O. Bagriantsev, Sviatoslav N. Kalfa, Theodosia A. Gallagher, Patrick G. |
| Copyright Year | 2017 |
| Description | Key Points There is heterogeneity in the clinical, laboratory, and genetic bases of HX. Alterations in PIEZO1 channel kinetics, response to osmotic stress, and membrane trafficking may contribute to channel dysfunction in HX. |
| Related Links | https://ashpublications.org/blood/article-pdf/130/16/1845/1403221/blood786004.pdf |
| Ending Page | 1856 |
| Page Count | 12 |
| Starting Page | 1845 |
| DOI | 10.1182/blood-2017-05-786004 |
| Journal | Blood |
| Issue Number | 16 |
| Volume Number | 130 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2017-10-19 |
| Access Restriction | Open |
| Subject Keyword | Medical Laboratory Technology Stress Xerocytosis Trafficking Osmotic Piezo1 Dysfunction Dysfunction in Hereditary Mechanisms of Piezo1 Journal: Blood (Vol- 127, Issue- 16) |
| Content Type | Text |
| Resource Type | Article |