NDLI: The Potentiality of Out-of-cycle Acute Leukemic Cells to Synthesize DNA

Content Provider	Scilit
Author	Stryckmans, M. D. P. Delalieux, M. D. G. Manaster, M. D. J. Socquet, M.
Copyright Year	1970
Description	The blood of 18 patients with acute leukemia was exposed to UV light. Within 2 hours, in all the patients (except one under chemotherapy), nearly 100 per cent of the leukemic blasts showed uptake of 3HTdR as a result of DNA repair replication. Similar exposures of CML blood white cells and chicken blood red cells to UV indicated that myeloid and erythroid cells have no capacity to repair DNA after they have stopped dividing as a result of maturation. This suggests that nonproliferating leukemia blasts are resting cells rather than "end cells."
Related Links	https://ashpublications.org/blood/article-pdf/36/6/697/575820/697.pdf
Ending Page	703
Page Count	7
Starting Page	697
DOI	10.1182/blood.v36.6.697.697
Journal	Blood
Issue Number	6
Volume Number	36
Language	English
Publisher	American Society of Hematology
Publisher Date	1970-12-01
Access Restriction	Open
Subject Keyword	Hematology Chemotherapy Uptake Leukemia Cml White Erythroid Cent Stopped Leukemic Nonproliferating Journal: Blood (Vol- 86, Issue- 6)
Content Type	Text
Resource Type	Article

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