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Improved results of treatment of adult acute lymphoblastic leukemia
| Content Provider | Scilit |
|---|---|
| Author | O'donnell, M. Linker, Ca Levitt, Lj Ries, Ca Link, Mp Forman, Sj Farbstein, Mj |
| Copyright Year | 1987 |
| Description | We designed a treatment program to improve the outcome for adults with acute lymphoblastic leukemia (ALL). Treatment included a remission- induction phase followed by intensive alternating cycles of non-cross- resistant chemotherapy and prolonged oral maintenance therapy. Eighty- one consecutive previously untreated patients were entered on this study. Ninety-four percent of patients entered complete remission. A Kaplan-Meier analysis predicts that 53% +/- 9% (SEM) of patients in remission will remain free of disease at 3 years. Neither age, sex, WBC count, nor immunophenotype had a significant effect on remission duration. This program of intensive cyclical chemotherapy has improved the disease-free survival of patients with adult ALL. |
| Related Links | https://ashpublications.org/blood/article-pdf/69/4/1242/364437/1242.pdf |
| Ending Page | 1248 |
| Page Count | 7 |
| Starting Page | 1242 |
| DOI | 10.1182/blood.v69.4.1242.bloodjournal6941242 |
| Journal | Blood |
| Issue Number | 4 |
| Volume Number | 69 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 1987-04-01 |
| Access Restriction | Open |
| Subject Keyword | Hematology Treatment Survival Chemotherapy Adult Remission Lymphoblastic Leukemia Intensive Acute Lymphoblastic Journal: Blood (Vol- 75, Issue- 4) |
| Content Type | Text |
| Resource Type | Article |