NDLI: Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation

Content Provider	Scilit
Author	Banno, Fumiaki Kita, Toshiyuki Fernández, José A. Yanamoto, Hiroji Tashima, Yuko Kokame, Koichi Griffin, John Miyata, Toshiyuki
Copyright Year	2015
Description	Key Points A protein S-K196E mutation reduced its activated protein C cofactor activity in recombinant murine protein S-K196E and in K196E mutant mice. Mice carrying a protein S-K196E mutation or heterozygous protein S deficiency were more vulnerable to venous thrombosis than wild-type mice.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635119/pdf
Ending Page	2253
Page Count	7
Starting Page	2247
DOI	10.1182/blood-2015-06-653162
Journal	Blood
Issue Number	19
Volume Number	126
Language	English
Publisher	American Society of Hematology
Publisher Date	2015-11-05
Access Restriction	Open
Subject Keyword	Hematology Protein Thrombosis Deficiency Thromboembolism Cofactor Murine Recombinant Venous Mice Carrying Exacerbated Journal: Blood (Vol- 130, Issue- 19)
Content Type	Text
Resource Type	Article

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